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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Aminooxy-PEG3-azide is a bifunctional PEG linker containing an aminooxy group and an azide handle for oxime ligation and azide-alkyne click chemistry. It is supplied as a liquid and is used for ADC and PROTAC linker synthesis, and for general bioconjugation and small-molecule assembly.
Bifunctional: aminooxy and azide reactive groups.
Peg3 spacer provides hydrophilicity and flexibility.
Suitable for oxime formation with carbonyls and CuAAC click reactions.
Purity typically 95.0%.
Stable when stored at -20°C; in solvent short-term storage at lower temperatures recommended.
Available in small research quantities, such as 5 mg.
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of PROTAC SGK3 degrader-1, a potent SGK3 degrader based on PROTAC technology. This product is for research use only.
Molecular weight: 296.40
Formula: C17H28O4
Appearance: Liquid (density: 1.031 g/cm³)
Color: Colorless to light yellow
Shipping: Room temperature in continental US
Pure form storage: -20°C for 3 years, 4°C for 2 years
In solvent storage: -80°C for 6 months, -20°C for 1 month
In vitro solubility: ≥ 100 mg/mL in DMSO
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BCN-exo-PEG3-NH2 is a BCN-functionalized PEG3 amine linker used in bioorthogonal conjugation and PROTAC linker synthesis. It provides a strained alkyne handle and a terminal primary amine to enable modular coupling strategies, and is commonly supplied in research-scale quantities at high reported purity.
Provides a strained alkyne (BCN) for rapid bioorthogonal click reactions.
Contains a PEG3 spacer for flexibility and improved solubility.
Features a terminal primary amine for amide or reductive amination conjugation.
Suitable for linker construction in targeted degradation and bioconjugation workflows.
Supplied in research-scale quantities with supplier-reported high purity.
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BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Purity: 99.94%
Molecular weight: 368.47
Chemical formula: C19H32N2O5
CAS number: 1841134-72-2
Appearance: Colorless to light yellow liquid
Density: 1.14±0.1 g/cm3
Used in PROTAC synthesis
Contains a BCN group for SPAAC reactions
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Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
Utilized in the synthesis of PROTACs.
Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
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Bis-PEG5-acid is a polyethylene glycol (PEG) based bifunctional linker with two terminal carboxylic acids. It serves as a hydrophilic spacer for PROTAC synthesis and bioconjugation, enabling formation of amide or ester bonds while improving solubility and flexibility.
Hydrophilic polyethylene glycol spacer.
Two terminal carboxylic acids for coupling reactions.
High purity suitable for research applications.
Solid form, convenient for storage and handling.
Available in laboratory pack sizes including 100 mg.
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Azido-PEG3-SSPy is a cleavable three-unit polyethylene glycol (PEG3) linker used for assembling antibody-drug conjugates (ADCs) and general bioconjugation. It contains an azide functional group enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN partners.
Cleavable disulfide linker for controlled release.
Azide-functionalized for CuAAC click chemistry.
Compatible with SPAAC (DBCO and BCN) reactions.
High purity suitable for conjugation workflows.
Multiple pack sizes available for research use.
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